Which statement best describes capsaicinoids in OC spray?

• A. OC spray irritates eyes, airways, and skin.
• B. OC spray disturbs only the sense of smell.
• C. OC spray paralyzes muscles instantly.
• D. OC spray neutralizes acids.

Answer: (A)

Capsaicinoids, the active irritants in OC spray, trigger a strong sensory irritant response by activating TRPV1 receptors on nerve endings in the eyes, nose, throat, and skin. This causes immediate burning, stinging, tearing, blinking, nasal drainage, coughing, and a sensation of airway irritation. Because of this broad irritation of eyes, airways, and skin, the effects are not limited to the sense of smell. They do not instantly paralyze muscles, and they do not neutralize acids; their primary action is irritant and inflammatory, leading to temporary incapacitation.